Melbourne Man In PrEP Trial Tests Positive to HIV

Tested Poz onPrEP

A man participating in a PrEP trial has tested positive to HIV at a Melbourne clinic.

It is not yet known whether the man has contracted a drug-resistant strain, or if something else is to blame, Fairfax Media reported.


There has never been a confirmed case of HIV resistant to PrEP in Australia.

A spokesman at The Alfred confirmed researchers were “reviewing the clinical details of a man who has tested positive to HIV while being a registered participant of the Victorian PrEPX study”.

Doherty Institute director and infectious diseases physician, University of Melbourne professor Sharon Lewin told Fairfax Media PrEP was extraordinarily effective and there was still an urgent need to expand access to PrEP nationally.

“We closely track circulating strains of drug resistant virus in the community,” she said.

“On average, 10 per cent of new diagnoses of HIV in Victoria are with a strain of virus that has evidence of drug resistance.

“I don’t think there is any reason for alarm here. PrEP works and any rare cases of failure need to be investigated fully so we fully understand why this can very rarely happen.”

Professor Lewin said once researchers at The Alfred have determined whether the man had been correctly and consistently taking PrEP, the HIV virus itself would be analysed for resistance.

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